Corpus evidence — top 10 passages

Most-relevant passages from the entire indexed corpus (67,286 paragraph chunks across YouTube transcripts, PubMed, arXiv, archive.org, Stanford Encyclopedia of Philosophy, OpenAlex, and more) ranked by semantic similarity (bge-small-en-v1.5).

1. 01 · _intake0.763

   **GEEK ALERT:** Great health is now a combination of parallel and serially wired new neural circuits that are created by our choices and substrates from food. Once you assimilate the building blocks ([Brain Gut-6](/brain-gut-6-epi-paleo-rx/)), then you can wired them together at the synapse’s using your hormones (cortisol and melatonin) to create new pathways to access parts of your brain that you were unaware of before. This is how you re-tap the great pharmacy in your head in the hypothalamus to get back to optimal. The story is not over just yet. With these newly wired circuits, [Hebbian le…

   _intake/kruse-blog-corpus/articles/brain-gut-15-creating-your-health-ipo.md

2. 02 · _intake0.763

   C. The new neural circuits created must wire together to become “hardwired” via Hebbian learning. This is done by optimal diurnal melatonin levels at night when we are chemically reduced. This is when the brain trims bad neural circuits and strengthens good ones to regain control of signaling. If melatonin is off you can not re wire a bad brain no matter what anyone tells you. This is why sleep is so critical to human biology.

   _intake/kruse-blog-corpus/articles/brain-gut-16-adrenal-fatigue-rx.md

3. 03 · yt0.752

   I'm Dr. John Cruz and today I'm going to be talking about how do we boost neurotransmitters. So the take-home message is that there's a couple different approaches to making more neurotransmitter. You could take more, make more of it, or you could ensure that what you already have lasts for a longer period of time. And I'll get into some of the details of why some of these approaches are simpler or easier or more likely to succeed in the brain. All of this is embedded in the context of why would you want to make more neurotransmitters. So there's a sort of ongoing for 50 plus years idea that m…

   yt/1GuVfh_KX94-boosting-neurotransmitters/transcript.txt

4. 04 · _intake0.750

   I learned empirically, the mitochondrial response of this neural retraining, could be followed and accounted for by the neuro-humeral response of the brain. This means that energy balance is codified in our hormone panel. That means the patients hormone status could be used as a detector to see how the system went awry and how it was responding to retraining over time. This was the most labor intensive time in synthesizing what I had learned about leptin. When I had I thought I had it all worked out in my own mind and in my notes, I became the guinea pig for this thought experiment. I used [qu…

   _intake/kruse-blog-corpus/articles/how-does-the-leptin-rx-work.md

5. 05 · _intake0.743

   **GEEKS AND NON GEEKS UNITE:** When I test people, I consistently find that their AM cortisol’s are low and this implies that their dopamine levels in their brain are also low too. To increase their central dopamine stores we can use a drug like **cycloset** and low dose **metformin** to help their blood sugars, protect their intestinal brush borders and lower the leakiness to ROS at cytochrome one. This increases their ability to clear superoxides created in their brain’s mitochondria. The science of this area involving neurons mitochondria is quite complex but I may tackle it down the pike f…

   _intake/kruse-blog-corpus/articles/brain-gut-11-is-technology-your-achilles-heel.md

6. 06 · _intake0.739

   Today, we are going to bend your mind a bit by explaining to you many of the things you might be believed as biologic truths published in biochemistry books today are in fact truths when certain environmental truths are held within a constant range. Yet, they change tremendously when certain factors are altered. Often the biophysical changes do not even have to affect the thermal coefficients of the biochemistry in the hypothalamus. Just the perception of the environmental change from the brain is enough to alter the chemistry as is the enzyme and proteins existed on the top of Mount Everest o…

   _intake/kruse-blog-corpus/articles/cold-thermogenesis-1-theory-to-practice-begins.md

7. 07 · yt0.739

   And the bloodb brain barrier prevents the simple passage of most larger molecules, special transporters to get certain amino acids and other chemicals into the brain that are essential for the brain. But again, just providing more of a precursor in the general body circulation does not guarantee that you'll have a higher concentration of that in the brain. And then even after you pass the bloodb brain barrier and get to the cells that are making whatever neurotransmitter, there's one last big cat and that is related to what's called the rate limiting step. And I'm going to jump back and use an…

   yt/1GuVfh_KX94-boosting-neurotransmitters/transcript.txt

8. 08 · _intake0.739

   Jack Kruse: Circadian Biology, Melanin & How To Heal You](https://www.youtube.com/watch?v=mfXkXp37oZM&t=3217) > we create and we need to think about that we need  to think about the organization of cells we need   to think about how melanin works with mitochondria  and really fundamentally why Rick was able to do   the things that he was able to do and then yo - **6** [must/causes/because] · `00:07:55.200` [Banned Neurosurgeon: Decentralize Your Health B4 It's Too La](https://www.youtube.com/watch?v=unUTOBIXvdc&t=475) > understand because I do think it's important…

   _intake/canon-claims-raw/BY-CONCEPT.md

9. 09 · _intake0.738

   We learn best when we move through our environment. Moving naturally is how humans learn best. This is why even those stricken with severe Alzheimer’s disease tend to improve cognitive performance with even mild exercise. Natural movement stimulates cortisol which increases neuron growth in our hippocampus to increase our ability to learn. Neural science tells us this and it is proven in how humans act and react to environmental stimuli to learn. But to LEARN things we must follow a certain path that is a series of positive or negative rewards that we code correctly in our brain… How we do it,…

   _intake/kruse-blog-corpus/articles/the-dopamine-rx-good-choices-or-bad.md

10. 10 · _intake0.738

    One of the ways we can counteract the normal loss of neurons is through neuro-plasticity. If we provide the brain with the proper substrates for optimal health and maintenance we can allow our genes to retool the brain while we sleep with the process of autophagy. This is the process by which a healthy brain can change to better cope with the environment it finds itself in now. This is precisely what epigenetics is. If an area of the brain is damaged and dysfunctional, another area can take over some of the function if we give it the tools to do so. As we fire a specific pathway repeatedly ove…

    _intake/kruse-blog-corpus/articles/your-gutneurotransmitters-and-hormones.md