Corpus evidence — top 10 passages

Most-relevant passages from the entire indexed corpus (67,286 paragraph chunks across YouTube transcripts, PubMed, arXiv, archive.org, Stanford Encyclopedia of Philosophy, OpenAlex, and more) ranked by semantic similarity (bge-small-en-v1.5).

1. 01 · _intake0.963

   > six things are important turns out one of the things that are in there is alpha msh alpha msh is the reason you have a tan malarian stimulating hormone correct Alpha msh was big so I was like that's the part the biggest part of the story as I started to realize okay how do we assimilate light so one of the things in neurosurgery that always confounded me in my training we never learned we know about the sen super cosmetic nucleus but we didn't learn that much about circadian biology at

   _intake/claims-allbranch/curated-low/circadian/006-six-things-are-important-turns-out-one-of-the-things-that-ar.md

2. 02 · yt0.776

   sunlight is vitally linked to the efficiency of both of those programs and apoptosis is when you get rid of bad engines in your body that don't make energy that's usually what happens in people that have diabetes cancer or the chronic diseases we talked about in the past and then there's another one which is called a autopsy and that process is when you recycle the bad engines rebuild them so that you can make good energy again and it turns out the neural hormone that all of you have heard of but never really understood totally from a basic science standpoint is melatonin melatonin controls al…

   yt/Wp7Dm2NJgmg-embracing-chaos-with-dr-jack-kruse-totalhealth-tv/transcript.txt

3. 03 · _intake0.774

   Melanocyte-stimulating hormone (MSH) is a collective name for a group of peptide hormones produced by the skin, eye, pituitary gland and hypothalamus in response to ultraviolet radiation. It plays a key role in producing colored pigmentation found in the skin, hair, and eyes of mammals. It does this by inducing specialized skin cells called melanocytes to produce melanin which stores UV light, until nightfall, when our bodies begin to harvest this light, to drive regeneration programs in our tissues. It will not work if blue light, specifically is being sensed by our surfaces. Melanocyte-stimu…

   _intake/kruse-blog-corpus/articles/time-12-adrenal-fatigue.md

4. 04 · _intake0.774

   MSH is intricately involved in the production of melatonin and endorphins in the brain. This is where my neurosurgery training really tied a lot of the pathophysiology together. Alpha MSH is cleaved off the larger POMC protein that is made in the brain. This quotient of the cleaving causes a lack of circulating endorphins in our CSF fluid, and this increases our perception of pain in all parts of our body. This is why Lyme and fibromyalgia patients have so many muscle aches and pains. Everything has a biochemical reason when you follow medicine from an evolutionary prism. This is a huge benefi…

   _intake/kruse-blog-corpus/articles/hey-lyme-disease-meet-leptin.md

5. 05 · yt0.769

   Well, and there's some there's some interesting tie-ins here to stuff I've discussed on the podcast before. Like I didn't know until about last year or so that there's nitric oxide stores in the skin and UV light exposure liberates those. Correct. So, what does that tell you that you just described the basics of the leptin prescription given what I'm giving you? You're you're beginning to jump forward in in the story because you just realized that if you're able to bind N to hemoglobin, you don't need as much oxygen. If you don't need as much oxygen, that means you don't need as much food beca…

   yt/67sLlXeMg2I-regenerative-energy-the-light-inside-you-jack-kruse-221/transcript.txt

6. 06 · yt0.768

   The key that you have to do, is you have to understand how sunlight controls the entire system, both in the eye and all the peripheral clock genes that are present. Guess what controls the peripheral clock genes? Melanopsin. Guess what controls the SEN? Turns out it's melanopsin again, because where did we find melanopsin first? It was in 1998. We didn't find it again in a new place until 2014, which will interest you as a cardiologist. It's in every artery of the body and the arterials. In 2017, that's when the seminal paper came that completed my Monk Who Sold His Ferrari story, because I th…

   yt/I537lQoiu5c-neuro-surgeon-by-day-mito-hacker-by-night-dr-jack-kruse/transcript.txt

7. 07 · yt0.767

   The the DNA side is actually where the light is stored. That's that we know. Oh, and the recursive clocks that are there between the storage of light in DNA ties to methylation patterns, ties to histones. That actually is the magic wand of epigenetics. Again, a light story. Yes. And we need to get science, basic science to those levels. So, like when I talk to a guy like Nick or Nick Lane, like they think I'm an alien because they don't even know this science already exists. And this is basic science. This is not this is this doesn't even require you blowing six neurons on understanding this s…

   yt/2njvFN-W4zc-red-light-blue-light-brain-damage-dr-jack-kruse-explains-wtf/transcript.txt

8. 08 · _intake0.767

   Jack Kruse: Circadian Biology, Melanin & How To Heal You](https://www.youtube.com/watch?v=mfXkXp37oZM&t=4640) > world and you like right in the middle of it uh  and having this update you know after 12 years   to discuss some of these things but the sad  part for me is you learned about me because   of all the luck and stuff you learned about  me because - **5** [never/because] · `01:17:24.480` [Dr. Jack Kruse: Circadian Biology, Melanin & How To Heal You](https://www.youtube.com/watch?v=mfXkXp37oZM&t=4644) > to discuss some of these things but the sad  …

   _intake/canon-claims-raw/BY-CONCEPT.md

9. 09 · _intake0.766

   Today we embark on new series. This series will begin to tie a lot of things together. Today’s blog is on a topic that has rarely been broached in the ‘*paleosphere*‘, because few understand how it relates to our biochemistry or the medical physics in our mitochondria. Do you know what ubiquitination is? Have a look here: [Link](http://www.ncbi.nlm.nih.gov/pubmed/19754430) It is, in my opinion, the most important thing that we do after our nucleic acids are expressed. It links to every known human disease.

   _intake/kruse-blog-corpus/articles/ubiquination-1-bio-hacking-altitude-suicide-loss-muscle-mass.md

10. 10 · yt0.765

    Maybe he's seen something before and he's pointing out to us. Mhm. It's true what he's saying. You don't make nitric oxide to inhibit you know, the four cytochrome unless you have UV light. That's how it happens. Nobel Prize was given for in 1998. You don't make Everybody knows you don't make vitamin D without UV light. That's different than 380 light. It's the light that's about 312 to 320. So I don't want you to think there's no need for that. And then I you know, the other thing I told you, you don't make melanin from palm C without UV light. UV light is the stimulus that causes the transla…

    yt/yo4h0B_JMQY-dr-jack-kruse-explains-how-sunlight-controls-leptin-melanin-/transcript.txt